With a name like HyperGenetic Killer Bee’s Fat Burner, we’re expecting something interesting. Today we’re going to look at this product and what it can do for you – alongside how it stacks up against its own claims of fat-burning power.
Read on if you’re looking to get a clear idea of what this supplement is all about: killer supplement, or just a lot of buzz?
About Killer Bee’s
Claiming to be the world’s strongest fat burner, Killer Bee’s is setting itself up as a fat burner that leans on potency. It’s a product that relies on a combination of three matrices: one for thermogenesis, one for energy, and one for suppressing appetite.
We’re going to judge its claims and examine how it relates to the market as a whole and how it compares to alternative products out there.
Killer Bee’s Supplement Facts
The three blends in Killer Bee’s – the Thermogenic Buzz Complex, the All-Day Euphoric Energy Complex and the Appetite Suppression Matrix – are designed to deliver what we look for in a good fat-burner: the ability to burn fat, reduce the negative fatigue-effects of losing weight, and control the appetite.
We’d also add that a good fat burner should spare at-risk tissues like bone and muscle, which could lose mass during a fat-loss diet.
Here’s a look at the ingredients list – even if there’s not much to gain from it, thanks to the use of annoying proprietary blends:
Directions for Use
The intended use is one capsule a day with water to ensure healthy digestion and reduce any digestive side-effect risk. We recommend a glass of water and taking it in the mid-morning for the best management of caffeine and its effects on your sleep quality.
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Vitamin/Mineral complex: B3, B6, and Chromium
These are essential vitamins involved in energy metabolism and cellular health, so the product is off to a good start. They’re functionally essential for the production of energy in cells and they are also common deficiencies in the modern diet.
Improving your B3, B6, and chromium levels won’t burn more fat, but they will keep your metabolism healthy and efficient. The result is continued, regular metabolism during the challenging times that fat-loss presents.
We’re going to discuss chromium some more later, since it’s specifically listed in the complicated proprietary blends this product provides.
This is actually billed incorrectly; it’s N, N-Dimethylphenylethylamine (N,N-DMPEA) and it’s half-way between a flavoring agent and a caffeine-like alkaloid. There are no real fat-burning benefits to this product outside of a possible, mild stimulant effect.
There’s not much documented reliable evidence of this compound on fat-loss. Even so, the dosage could be anything, so we’re not too concerned for its possible effects – especially if it’s being used for flavoring.
Norcoclaurine HCL , also known as Higenamine, is a compound that is included because it’s structurally similar to ephedrine, though there’s no real evidence that it works to burn fat in the same way.
Of course, ephedrine is a banned substance due to its dangerous side effects, and higenamine may well be on the same track. It is already banned by WADA and it is on the FDA’s Dietary Supplement Ingredient Advisory List, meaning it ‘does not appear to be a lawful ingredient in dietary supplements’. The FDA recommend that customers avoid purchasing products which include higenamine, – especially since most doses are not accurate among supplement manufacturers.
The exact mechanism of Norcoclaurine/Higenamine is unclear right now – as is the dose – but it does introduce another possible side effect if it’s similar enough to ephedrine. This is especially concerning in relation to the overall stimulant load in Killer Bee’s and its shared – negative – effects on cardiorespiratory health.
This is a low-level stimulant in the same way that caffeine is. It’s not affected by your caffeine-tolerance, however, so it’s going to have a slightly different effect. It’s a good way of diversifying the use of stimulants in the product.
Obviously, we can’t say how much there is since it’s hidden behind a proprietary blend. This is a greater issue with stimulants since your tolerance and sensitivity can vary significantly from the next person and you don’t know what you’re getting with this product.
The dose of a stimulant also influences things like your metabolic and cardiac response to the product. This is a concern if you have existing medical conditions that make you vulnerable to stimulant doses and to the negative health effects they could produce.
This is just another reason that we dislike proprietary blends – and that list continues to grow as we look through the ingredients of this product. They’re good ingredients but only in the context of effective, well-balanced dosages!
This is a source of a powerful phenolic compound called Salicylic acid which is considered to be one of the most important, safest forms of nutrient-medicine for skin health.
It’s a common compound for skin health and is included in anti-acne medications, for example. The inclusion of this product doesn’t make us think fat-burning, but it is a generally-useful compound to get into your diet.
It is antiseptic and controls bacteria levels, so it can be useful for digestive regulation. These are cool secondary effects but they’re not likely to be enormous due to the (likely) low content of this compound in this product.
Cayenne Pepper Extract
This is a classic for fat-burner products and with good reason; it produces the kind of thermogenic effect we’d like to see in the ‘thermogenic buzz’ complex. It’s a time-honored ingredient that has both antioxidant effects and fat-burning thermogenesis effects.
The result is an ingredient that is both good for your health and specifically directed towards fat loss. It makes you use more calories which allows you to burn more fat, which is fantastic.
Of course, there’s a problem here with the proprietary blend – we have no idea what the dose is. This is a significant concern since the dosage determines how effective any ingredient is going to be and especially a thermogenic compound.
Overall, a good ingredient choice but we can’t say just how effective it could be.
This is another analogue for capsaicin (the active ingredient in cayenne pepper) which we have already established as a great ingredient choice. It carries the same antioxidant and thermogenic benefits, which can be great, but we still have no idea of the quantity of effect.
This is a great ingredient choice even if it’s not clear how it may perform in combination with – or relative to – standard capsaicin.
It also seems to have some mild contributions to endurance performance.
All Day Euphoric Energy Complex
This is a predictable part of most fat-burners, it’s a common choice for increasing calorie usage and it contributes to other factors like perception of energy and combatting fatigue. It does all the things we outlined in the start of this piece as the desired results of an effective fat burner – except for sparing muscle.
The dose of caffeine makes a significant difference, however, and this is a concern for the proprietary blend of this product. We are mentioning it repeatedly because it’s one of the most annoying drawbacks: this product could be great, but we can’t say because we don’t know what’s in it.
There’s a minimum caffeine intake of around 200m-250mg that produces significant performance and metabolic benefits, but we can’t say if this product meets that threshold. Equally, we can’t say how far it goes towards the 450mg limit that the FDA recommends for stimulant intake.
As a result, you’re out of control of what you’re putting in your body since you can’t make an informed or measured choice. This is a heavy burden for an otherwise-good product so far!
In many ways, this is a fantastic addition because it offers a more digestively-stable form of caffeine. It ensures there’s variety in your stimulant load and also protects you from some of the digestive drawbacks of caffeine like potential cramping or, predictably, diarrhetic effects.
The result is a better form of caffeine for many people and – in replacing normal caffeine – it offers a benefit. However, as before, the relation of dosage to effect is huge – especially since malic acid (malate) replaces some of the caffeine in the dosage.
It’s a good ingredient choice but the dose is likely low, even if we can’t confirm the actual numbers.
Phenylethylamine is a common precursor to important hormones in the mood and fatigue processes. These include things like dopamine, which are important for happiness at the chemical level.
However, the struggle is that this kind of compound tends to be digested and broken down into less useful compounds in the body. Consuming it – even in the Beta-Phenylethylamine HCL form – doesn’t guarantee you’re getting it where it needs to be.
On top of that, this adjustment of the chemical structure reduces effective dose per gram and – since we don’t know the dosage – it’s possible it could be underdosed. The result is a pretty unreliable effect at best.
This is basically the nutritional raw material for serotonin, which is crucial for regulating both mood and fatigue. These are cool effects and we like seeing 5-HTP in supplements because they contribute to better management of the feeling of energy and mood during a weight-loss diet.
This is a good contribution and we’re glad to see this kind of secondary support. It’s an often-overlooked factor but this ingredient choice helps to bolster you during difficult times when it’s easy to feel drained and weak.
Hordenine (another form of/name for Norcoclaurine) is another stimulant, similar in structure to stimulants found in bitter orange (synephrine, which in turn is similar to ephedrine). WebMD warns it is ‘possibly unsafe’ when taken by mouth as it may have the same side effects as synephrine, namely high blood pressure and rapid heartbeat.
We’re not thrilled with this addition to the Killer Bee’s formula. It seems careless to include potentially risky ingredients like Hordenine, especially when their benefit to fat loss has not been proven. There’s simply not enough science to say if it works, how it works, or how much benefit you could get from it. As a result, we’re not confident this does anything just yet.
As with the inclusion in the previous matrix, the risks are worth considering in the context of overall stimulant risk, but the benefits are unconfirmed.
Tyrosine is cool and this form is more effective in the body – as well as contributing acetyl groups for other processes.
The result is a mental performance and support amino acid that digests well. The effects of tyrosine are primarily anti-fatigue and contribute to mood, which makes it a great choice for this energy complex.
The dose is a total mystery, like every other ingredient in this product, but the choice is a good one!
Appetite Suppression Matrix
This is pretty much a flavoring since it is the active flavor ingredient in ginger and other foods. It carries many of the antioxidant effects we associate with ginger, so it provides a modest level of cellular health support.
This isn’t a fat burning compound so we’re not too concerned, but the additional health benefits are a welcome and beneficial addition.
This is a useful fatty acid that produces short-term antioxidant benefits, but not long-term ones. It also modestly improves blood sugar levels but – again – only in the short term.
This will produce some useful changes at the start of use, but they won’t continue for long and you shouldn’t rely on them!
This is a ridiculous choice along almost every possible metric. Raspberry ketones may have been popular at one time, but we know that they do not produce reliable fat loss in humans – and all the supporting research is in rats.
The difference is that humans don’t react to raspberry ketone like rats do and – to compare the clinical amounts – you’d need a ridiculous amount of ketones. Needless to say, you’re not getting that from this product!
This is a controversial choice since yohimbine does seem to help burn fat, but also has implications for increased stress and anxiety response. This means that, in some ways, you’re trading the security of your mental health for fat loss – not a trivial risk!
This is a concern for some of our favorite effects of a good product, since increased stress and anxiety also contribute to reduced muscle-sparing and workout recovery. These are important factors for how your body changes during a fat-loss diet and they can influence what your final result is in terms of strength and muscle mass.
It is an essential mineral and it’s important for thyroid function, making it relevant to fat loss.
Chromium is about preventing deficiency, however, and won’t boost fat loss by itself. Rather, deficiency can prevent fat loss so supplementary chromium is one way of avoiding this kind of metabolic problem.
This is a good addition but it’s important to remember it won’t do much by itself. Thyroid health can be supported and regulated but more isn’t necessarily better, so this isn’t an active ingredient for most people.
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Killer Bee’s Formula Analysis
We can’t say anything conclusive about Killer Bee’s formula because proprietary blends ruin products and make reviews impossible. There’s no information for you or us to look at and determine how effective a product is going to be. This is the kind of thing that we hate because this product could be pretty good if we could get a clear picture of the contents.
In nutrition, dosages are crucial for effect. The proprietary blend means we can’t see them in this product and it’s totally plausible that everything is underdosed and ineffective as a result. There are some cool ingredient choices here, but they’re hamstrung by possibly ineffective doses and the general manufacturer ethos that you don’t need to know what you’re putting in your body.
A good supplement manufacturer would be proud of their ingredients and would value customer’s right to know and choose in an informed way! HyperGenetic have decided to not offer this crucial information.
This is something that we will always treat skeptically: if your dosages are good, why hide them?
Benefits of HyperGenetic Killer Bee’s Fat Burner
The benefits of this product are hard to establish when there’s no information on the ingredients and their quantities. These make for very difficult choices since there’s no way you could understand what you’re getting as a consumer – and we can’t review a product that has no dosages as well as we’d like!
At the very least we can say there are likely to be some benefits to the way you feel while using this product. The energy and mood components are effective by degrees; smaller doses mean smaller effects.
However, we can’t speak to the effectiveness of the ingredients that it relies on for fat-burning effects, since these could be effective or totally impossible to notice, all depending on how much you consume.
The benefits are limited at best, and we’re sad to see this because the sheer variety of ingredients is cool. This could, of course, just mean diluting of the active ingredients and thus a low-quality experience.
Sadly, we just can’t say how effective HyperGenetics’ Killer Bee’s Fat Burner is – nor what effects it will have – only those which are possible.
Who Should Use It?
We can’t recommend this product since we have a strong stance on the importance of customer informed choice and this product doesn’t allow you that. It’s an example of the potential to be a good general-use fat burner but no more.
The potential is the sad part because we can’t recommend a product without a grasp on its dosages and effects. If we knew more about these numbers, we could recommend it widely, but for now the only people who should use this product are those who like surprises – because that’s all we can confirm!
Any Potential Side Effects with Killer Bee’s?
We can’t say for certain – there are a few places where side effects might become a relevant consideration. One of these is stimulant content, while another is the presence of Norcoclaurine and its structural similarity to ephedrine.
We’re not clear on the stimulant load since there’s no clear ingredient dosages. Given the variety of stimulants in this product, it’s clearly going to be a concern – and you should watch out if you’re stimulant-sensitive.
The inclusion of Norcoclaurine introduces another level of “is this going to be a problem?” concern – it’s similar to ephedrine but may or may not work similarly. The result is potential negative effects but without much clarity because of low evidence and unclear doses.
The proprietary blends really ratchet up the risk of this product as there are no disclosed risks – so you can’t decide if it fits your dietary needs or not!
See the Top Ranked Fat Burners
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Killer Bee’s Summary
- Interesting ingredient choices and variety
- Some great choices like N-Acetyl-L-Tyrosine and Dicaffeine Malate
- Sketchy choices like Norcoclaurine
- Potentially heavy on stimulants – though it’s impossible to tell
- Proprietary blends tend to disguise underdosed or token ingredients
Pricing & Where to Buy
Our buying advice is to consider your alternatives because a manufacturer who doesn’t disclose their ingredients is one that doesn’t care about your rights as a consumer.
If you decide you want to take a risk with this product and its uncertain ingredients/doses, we recommend getting it from a direct source like NetNutri, where you can get the convenience of regular sales and shipping.
The RRP is $60 but this kind of buying option sees this product go for around $35. We don’t think it’s earned your money, but that’s for you to decide!
HyperGenetic Killer Bee’s Fat Burner Review: Conclusion
This is a good example of a product that could’ve been good but fell prey to its manufacturer’s dependence on proprietary blends. This is a ridiculous way to ruin a good product and we’re legitimately disappointed.
The selection of ingredients is interesting and varied, but the overall effects are difficult to interpret in light of the total lack of dosage information. This can make the difference between effective choice and useless filler ingredients.
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