If you want a simple nitric-oxide-boosting bodybuilding supplement, Bodybuilding.com Signature Citrulline should exceed your lofty expectations, as you’ll find out in this review.
About Bodybuilding.com Signature Citrulline
Bodybuilding.com Signature Citrulline “supports increased blood flow” and “promotes muscle pumps and exercise performance,” per its official website. Formula notes:
- Two grams of l-citrulline per serving. This is about as simple as it gets.
- Excellent transparency. Manufacturer breaks down all of the ingredient amounts.
- Bodybuilding.com product. Arguably the world’s most popular bodybuilding website.
Bodybuilding.com Signature Citrulline Supplement Facts (Unflavored, 200 grams) |
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Serving Size: 1 Scoop (2 g) Servings Per Container: 100 |
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Nutrient | Amount Per Serving | % Daily Value |
L-Citrulline | 2 g | † |
Other Ingredients: None. | ||
Directions: As a dietary supplement, add 1 scoop (2 grams) to your favorite beverage 1-2 times daily. To boost your workout, combine with Signature Pre-Workout or, for maximum post-workout benefits, combine with Signature Creatine and BCAA. |
Bodybuilding.com’s Signature Vasodilator
We’ve reviewed some supplements from the Bodybuilding.com Signature product line here on B5:
- Bodybuilding.com Signature Multivitamin
- Bodybuilding.com Signature Amino Plus Energy
- Bodybuilding.com Signature BCAA
- Bodybuilding.com Signature Pre-Workout
- Bodybuilding.com Signature 100% Whey Protein
It’s a solid supplement line for the most part. However, most of these products aren’t perfect. The main culprit: fillers such as the artificial sweetener sucralose. We had high expectations for Bodybuilding.com. After all, it’s arguably the world’s most popular fitness website. The company is better than this.
On that note, we’re hoping Bodybuilding.com Signature Citrulline can make a resounding statement. The manufacturer claims this supplement “supports increased blood flow” and “promotes muscle pumps and exercise performance,” per its official website.

Bodybuilding.com Signature Citrulline can help increase your muscle pumps at the gym and then some.
When you’re talking about citrulline, that’s just the proverbial tip of the iceberg. It is one pre-workout supplement ingredient which has gained serious traction over the years. You may find yourself adding it to your bodybuilding supplement stack sooner than later.
Formulation, 2 grams
Bodybuilding.com Signature Citrulline joins the ranks of KAGED MUSCLE PURCAF CAFFEINE and Olympian Labs Melatonin Fast Dissolve as some of the simplest supplements on the market today. If you look at the supplement facts, they have only one major ingredient.
As for Bodybuilding.com Signature Citrulline, it has two grams of l-citrulline per scoop. That’s it. No other fancy ingredients. No fuss, no frills. Just pure citrulline – a non-essential amino acid and na If you’re a huge fan of this component, you have to be excited – you will reap its full benefits without those nasty fillers and dirty ingredients. It just doesn’t get any better than that.
“Citrulline is a naturally-occurring amino acid that supports the production of the amino acid arginine. Increased arginine leads to increased nitric oxide (NO), a vasodilator that opens up blood vessels and increases oxygen and blood flow throughout your body. That’s what fans refer to as pumps,” per the manufacturer’s official website.
To substantiate this, the journal Biomarkers in Toxicology published a study in 2014 (via ScienceDirect.com) which says, “Citrulline has been shown to be an effective substitute to restore NO (nitric oxide) production in situations of limited Arg (arginine) availability and Cit (citrulline) supplementation holds promise as a therapeutic adjunct in clinical conditions associated with Arg/NO deficiency and/or endothelial dysfunction.”
Between l-arginine and l-citrulline, we recommend you go for the latter. L-arginine has poor absorption properties. Not only that, but it may cause gastrointestinal discomfort. Plus, its nitric-oxide-boosting effects don’t last as long as l-citrulline’s. We’re glad Bodybuilding.com Signature Citrulline uses the better vasodilator.
Aside from its ability to ramp up muscle pumps, citrulline also helps increase exercise endurance. “Citrulline also keeps you going strong by helping your body eliminate ammonia. Ammonia, a byproduct of protein synthesis, causes exercise-related fatigue,” per the company’s official website.
The University of Rochester Medical Center’s official website confirms citrulline does remove ammonia from the body. Plus, it helps regulate immunity and increase energy levels. Bear in mind these are benefits which are vital to bodybuilding enthusiasts. Heavy training may take a toll on one’s recovery time, immune system, and energy levels. Supplementing with citrulline should give you an edge at the gym.
“Studies have shown improved power output, oxygen consumption, and exercise performance with just 2.4 grams per day over an eight-day period,” per the manufacturer’s official website. The company cites two studies which the Journal of the International Society of Sports Nutrition and the Journal of Applied Physiology published in 2014 and 2015, respectively. That’s solid scientific evidence right there.
The good news: researchers who published a study in the Journal of Applied Physiology’s October 6, 2015 issue (via the Natural Health Research Institute’s official website) discovered more exciting benefits of citrulline other than those related to exercise performance. It says, “Chronic supplementation with l-citrulline might represent a practical, dietary intervention to reduce blood pressure and enhance oxidative metabolism and exercise performance in young, healthy adults.” If this doesn’t excite you, we certainly don’t know what will.
We’re confident you will reap all of these impressive benefits when you supplement with Bodybuilding.com Signature Citrulline. It’s a simple yet solid product with great transparency and a clean ingredient profile. A simple product always gets our attention. You don’t need fancy – and useless – components to get customers’ attention. Sometimes, all it takes is one ingredient to do the job. Bodybuilding.com Signature Citrulline is the perfect epitome of such a product.
Let’s check out the formula ingredients:
- L-citrulline, 2 g: A non-essential amino acid and natural ingredient of watermelon which helps increase nitric oxide levels for increased vasodilation, blood flow, muscle pumps, and exercise performance; improved nutrient uptake, and healthier blood pressure levels.
Formula Analysis
If you want to boost your workout results, Bodybuilding.com Signature Citrulline is the way to go. If you haven’t reaped the impressive benefits of this powerful amino acid, now is the time to do so.
There’s also no better way to do it than with this particular supplement. It’s so downright simple, it’s mind-boggling. Will two grams of l-citrulline per serving go a long way? Absolutely.
First off, there are many bodybuilding products with scant amounts of l-citrulline. A good example is MuscleTech Platinum Amino + Energy, which has just 125 milligrams of l-citrulline per scoop. That much won’t give you insane muscle pumps, for sure. If this is what you want, try Dymatize Pre W.O. or Nutrex OUTLIFT AMPED, which both have an otherworldly eight grams of citrulline malate per serving (this is l-citrulline bonded to malic acid for increased exercise endurance).
Granted, Bodybuilding.com Signature Citrulline’s l-citrulline amount is nowhere near that level. However, popular nitric-oxide-boosting products such as KAGED MUSCLE CITRULLINE have the same l-citrulline levels (two grams per scoop). Customers have given this supplement excellent grades online. We see no reason why Bodybuilding.com Signature Citrulline cannot receive the same amount of praise.
You can be sure two grams of l-citrulline per serving can help increase blood flow, vasodilation, exercise endurance, and muscle pumps; improve nutrient uptake, promote healthy blood pressure levels, and keep ammonia levels in check.
On the other hand, the manufacturer does an excellent job in terms of transparency – it reveals all of the ingredient amounts. You won’t find any shady proprietary blends in Bodybuilding.com Signature Citrulline.
This supplement also has no dirty ingredients or fillers. Nowadays, it’s not uncommon to spot a bodybuilding product with relatively clean ingredients, only to discover the manufacturer laced it with sucralose or artificial food colorings. That’s not good at all. Bodybuilding.com Signature Citrulline is like a breath of fresh air. We love it.
Just about the only minor downside is its unknown reputation. We’re not worried about it. In due time, this supplement will earn the respect of many bodybuilding aficionados.
After a thorough analysis, Bodybuilding.com Signature Citrulline is an up-and-coming player with a tremendous upside. If you want a nitric oxide fix or an added kick for your pre-workout supplement, this is a great choice.
Bodybuilding.com Signature Citrulline Benefits
Bodybuilding.com Signature Citrulline “supports increased blood flow” and “promotes muscle pumps and exercise performance,” per its official website.
Who Takes It?
The manufacturer intended Bodybuilding.com Signature Citrulline for healthy and active individuals who want to increase blood flow, nitric oxide levels, vasodilation, muscle pumps, and exercise endurance; shorten recovery time, and achieve their daily fitness goals.
Any Side Effects?
While Bodybuilding.com Signature Citrulline has no glaring side effects, please consult your doctor if you feel doubtful about any of its ingredients.
The manufacturer also issues a warning:
Bodybuilding.com Signature Citrulline Review Summary
Pros
- Two grams of l-citrulline per scoop. Powerful nitric oxide booster which helps increase blood flow, muscle pumps, exercise endurance and promotes healthy blood pressure levels.
- Excellent transparency. Manufacturer reveals all of the ingredient amounts.
- Clean ingredients. You won’t find any fillers here.
- Bodybuilding.com product. Arguably the world’s most popular bodybuilding website.
Cons
- Unknown reputation. New player which should gain serious traction as time goes by.
Pricing & Where to Buy
- 1 200-gram container (100-Day Supply): $16.99
- Available online and in retail
Final Word on Bodybuilding.com Signature Citrulline
If you need a powerful nitric oxide fix or an added kick for your pre-workout supplement, Bodybuilding.com Signature Citrulline is an excellent choice. It’ll provide you with two grams of quality citrulline for more muscle pumps ando other key benefits at the gym.
We highly recommend you buy Bodybuilding.com Signature Citrulline. We’re 100 percent certain it will help you achieve your fitness goals. Go get yours today.
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