Every superhero needs a side-kick.
Just imagine a Batman without Robin.
Joker without Harley.
Kevin Durant without Russell Westbrook (Too soon? Also, who’s the side-kick there?). That’s essentially what we’re looking at here between Nugenix Ultimate Testosterone and its estrogen-blocking side-kick Nugenix Estro-Regulator. While Nugenix UT has the T covered, Estro-Regulator is intended to keep down the E… Key word: intended.
After reviewing Estro-Regulator, we’re wondering if some superheroes are better off superheroing solo.
About Nugenix Estro-Regulator
Based on the Nugenix T-booster, Nugenix Estro-Regulator is coming into this review with the bar set pretty high. At the least, if Estro-Regulator doesn’t work for “regulating estrogen,” then at least you still have some qualified T-boosts under the Nugenix name. Formula notes:
- Estrogen Regulation: Boosting the test is important, but you also need to regulate the est (as in estrogen) for optimized male manliness.
- Diindolylmethane: Nugenix’s E-blocking star is a hugely popular ingredient in T-booster stacks, but is surrounded by questionable research.
- Not a T-Booster: Estro-Regulator completely does away with the testosterone boosters, minus Chrysin which… well, doesn’t do much for T.
Nugenix Estro-Regulator Supplement Facts
|Serving Size: 2 Capsules
Servings Per Container: 30
|Ingredients||Amount Per Serving|
|Vitamin E||10 IU (33% DV)|
|Polygonum cuspidatum Extract (Root) (50% Trans-Resveratrol)||300 mg|
|Diindolylmethane (DIM)||100 mg|
Gelatin, Rice Flour, Stearic Acid, Magnesium Stearate, Silica
Adults take two (2) capsules in the morning with water.
Nugenix Estro Regulator is straight E-blocks & zero T-boosts.
Vitamin E, 10 IU
Not an outright surprising addition to this formula, but neither is it outright exciting.
Some sources suggest Vitamin E helps with strength & athletic performance (although, research seems to indicate otherwise). Other studies state that Vitamin E (with its usual partner Vitamin C) may actually diminish athletic health.
In regards to estrogen, the “facts” are less clear—namely due to the overwhelming attention to women’s health in the research. Overall, the vitamin seems valuable in protecting against excessive estradiol levels and might aid sex hormone status—but that might be all-across-the-board (i.e. Vitamin E aids T & estrogen).
Chrysin, 500 mg
By this point, Chrysin is sold in T-boosters simply for its reputation of being sold in T-boosters. Because the science doesn’t quite hold up:
- On one hand, it does possess the bio-actions required to upregulate T-synthesis.
- Yet, those bio-actions are only effective when Chrysin is directly injected into the testes.
Orally consuming Chrysin essentially does nothing for T levels and we can’t imagine none of y’all are too excited about needling your scro-sacks (no judgment, though, if we’re wrong).
Polygonum Cuspidatum, 300 mg
The key constituent here: Resveratrol.
Most commonly associated with the health benefits of red wine, Resveratrol is a powerful antioxidant with plenty of anti-inflammatory benefits, but its anti-E action is questionable. Less questionable than the previous ingredients, because it does seem to enhance overall health—but its bio-actions seem to do nothing for testosterone.
Diindolylmethane (DIM), 100 mg
We understand the appeal of DIM:
- It’s sourced from health-ass vegetables.
- Research suggests it inhibits aromatase—the enzyme responsible for converting T to estrogen.
Yet, not all of the research points to DIM having this action in men, with some studies actually showing decreases in T levels, along with other male sex hormones. This is why we classify DIM as a “T-Booster to Avoid” on our BIG LIST of T-Boosters.
Nugenix Ultimate Testosterone is a damn good, potent ass T-booster.
Nugenix Estro Regulator is a… pretty nifty E-blocker, maybe.
It has a couple conceptually sound estrogen blockers (Diindolylmethane, Resveratrol) that might work for men, but who frickin’ knows at this point. Then we have Vitamin E & Chrysin—the latter of showing T-boosting action in rats only when directly injected into the testes, the former supplying more of that “who frickin’ knows” flavor.
On the whole, we have a giant question mark of an estrogen blocker: Maybe it works? Maybe it doesn’t? Maybe inject it into your balls and see what happens?
At the least, we can say that the ingredients seem adequately dosed, so you won’t have to worry about them not working due to under-dosage. The Polygonum Cuspidatum supplies some premium-level Resveratrol. Good job there.
Otherwise, we’d only recommend this T-booster (E-blocker*) if you’re considering supplementing this Diindolylmethane everyone is talking about and you like the ingredient additions here that might work, but, again… who frickin’ knows.
Nugenix Estro-Regulator Benefits
The unwritten rule: You need to at least bulletin point 3 benefits on your supplement for it to qualify as a supplement. Nugenix Estro-Regulator gets around this by bulletin pointing the essentially same benefit 3 times:
- Support Estrogen Regulation
- Reduce Aromatization of Testosterone
- Support Hormone Balance
In theory, reducing aromatization of testosterone supports estrogen regulation, in effect supporting overall hormonal balance. If this works, then Nugenix Estro-Regulator makes for a valuable supplement with which to supplement your T-booster supplements.
It’s a supplement for supplements!
…We’re so God damn clever.
Who Takes It?
Nugenix Users. We can’t imagine this supplement standing up on its own without the added support of Nugenix’s primary T-boosting formula. As such, Nugenix Estro-Regulator is intended to stack with the Nugenix line of T-boosters for optimum effect.
Any Side Effects?
Nope. At least there have been none reported and the ingredient profile doesn’t draw any RED flags for us. In actuality, Estro Regulator comes across as a rather healthy formula thanks to the Polygonum addition, which supports all-around bodily health.
Nugenix Estro-Regulator Summary
- E-Regulation. Considerable addition to any heavy T-booster regimen.
- Resveratrol. Solid anti-inflammatory action with potential E-blocks.
- Adequate Dosages. Everything seems appropriately dosed.
- Questionable Ingredients. Vitamin E, Chrysin, DIM… That’s 3 of 4 ingredients.
- No T-Boosts. At least throw in some T-boosting vitamins & minerals here.
- Expensive. For a short formula intended to be stacked, $49.99 is too much.
Pricing & Buying Info
- 1 Bottle (1 month): $49.99
- Available online and in retail stores
Final Word on Nugenix Estro-Regulator
Compared to Nugenix’s original formulation, Nugenix Ultimate Testosterone is a huge step forward. And now the series seems to be taking a step backwards with Nugenix Estro-Regulator’s questionably ineffective formula. Luckily, Nugenix UT is still a T-boosting option with which to consider stacking Nugenix Estro-Regulator for additional (potential) E-blocking support.